2-chloro-4-[[2-(diethylamino)-5-methoxyphenyl]methyl]-N,N-dimethylaniline - Names and Identifiers
Name | (3R)-1,2,3,4-tetrahydroisoquinolin-3-ylmethanol
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Synonyms | (R)-1,2,3,4-Tetrahydroisoquinolyl-methan-3-ol (3R)-1,2,3,4-tetrahydroisoquinolin-4-ylMethanol (3R)-1,2,3,4-Tetrahydroisoquinolin-3-ylmethanol (3R)-1,2,3,4-tetrahydroisoquinolin-3-ylmethanol (R)-(1,2,3,4-Tetrahydroisoquinolin-3-Yl)-Methanol (R)-(1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL)-METHANOL (R)-(+)-1,2,3,4-Tetrahydro-3-isoquinolinemethanol (R)-(1,2,3,4-tetrahydroisoduinolin-3-yl)-Methanol 3-isoquinolinemethanol, 1,2,3,4-tetrahydro-, (3R)- 3(R)-HYDROXYMETHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE 2-chloro-4-[[2-(diethylamino)-5-methoxyphenyl]methyl]-N,N-dimethylaniline
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CAS | 62855-02-1
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InChI | InChI=1/C10H13NO/c12-7-10-5-8-3-1-2-4-9(8)6-11-10/h1-4,10-12H,5-7H2/t10-/m1/s1 |
2-chloro-4-[[2-(diethylamino)-5-methoxyphenyl]methyl]-N,N-dimethylaniline - Physico-chemical Properties
Molecular Formula | C10H13NO
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Molar Mass | 163.22 |
Density | 1.081±0.06 g/cm3(Predicted) |
Boling Point | 307.9±27.0 °C(Predicted) |
Flash Point | 147°C |
Vapor Presure | 0.000305mmHg at 25°C |
Appearance | White powder |
Color | White |
pKa | 14.57±0.10(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.549 |
MDL | MFCD02684327 |
2-chloro-4-[[2-(diethylamino)-5-methoxyphenyl]methyl]-N,N-dimethylaniline - Risk and Safety
Safety Description | 24/25 - Avoid contact with skin and eyes.
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HS Code | 29339900 |
2-chloro-4-[[2-(diethylamino)-5-methoxyphenyl]methyl]-N,N-dimethylaniline - Introduction
(3R)-1,2,3, Br is an organic compound whose chemical formula is C10H13NO. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow solid
-Melting point: about 60-65 ℃
-Thermal stability: Soluble in a variety of organic solvents, such as alcohols and ethers
-Optical rotation: it is dextrorotatory, and its symbol is ()
-Molecular structure: has a tetrahydroisoquinoline ring and a hydroxymethyl functional group
Use:
-Used in organic synthesis: As a chiral intermediate, it can be used in various organic synthesis reactions, especially the synthesis of Strick compounds (Strick compounds).
-Drug research: In drug research, it can be used as an intermediate for the synthesis of chiral drugs or as a chiral catalyst.
Preparation Method:
The preparation method of (3R)-1,2,3, can be achieved by chiral redox reaction. A common synthesis method is the use of triphenylphosphine (triphenylphosphine) induced cyclopentadiene redox reaction, after a multi-step reaction to obtain the target product.
Safety Information:
The safety of this compound has not been reported in detail. In general, however, proper laboratory practices need to be followed when handling organic compounds to ensure safety. Direct contact with skin and eyes should be avoided, and use in a well-ventilated place should be ensured. If exposed or inhaled, wash or seek medical help. Appropriate personal protective equipment should always be worn when performing chemical synthesis or laboratory operations.
Last Update:2024-04-09 20:45:29